Dopamine reuptake inhibitor
- ↑ extracellular dopamine
- Wakefulness, focus and, at high DAT occupancy, reinforcement
- Rapid onset + high occupancy → greater abuse potential
- Inhibits dopamine transporter (DAT)
- No clinically available selective DRIs
- ➔ they are NRIs also DRI DRI DAT
Drugs with this mechanism (32)
Methylphenidate XR (Adhansia)
Bupropion hydrobromide ER
Methylphenidate XR (Aptensio)
Armodafinil
Benztropine
Bupropion
Centanafadine
Cocaine
Methylphenidate ER (OROS)
Methylphenidate XR-ODT
Methylphenidate patch
Desmethylsertraline
Dexmethylphenidate
Dexmethylphenidate XR
Bupropion XL 450 mg
Hydroxybupropion
Methylphenidate ER evening-dosed
Methylenedioxypyrovalerone
Methylphenidate CD
Methylphenidate
Methylphenidate chewable
Methylphenidate oral solution
Methylphenidate SR
Modafinil
Methylphenidate ER chewable
Methylphenidate ER suspension
Methylphenidate ER (Relexxii)
Methylphenidate LA
Solriamfetol
Bupropion SR
Bupropion XL
Bupropion SR (smoking cessation)
All mechanisms · Open DAT inhibitor in the interactive console ↗