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Methylenedioxypyrovalerone

MDPV

Methylenedioxypyrovalerone ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Methylenedioxypyrovalerone ballicule

What it isSynthetic cathinone and potent dopamine reuptake inhibitor; illicit "bath salts".

Why this oneIt is more potent at DAT than cocaine, which explains the severity of the agitation seen.

What limits itExcited delirium, hyperthermia and rhabdomyolysis. Not detected on routine drug screens.

Methylenedioxypyrovalerone molecular structure (skeletal formula)
Molecular structure: Methylenedioxypyrovalerone

FDA-approved for

NO BOXED WARNINGS

Principal riskExcited delirium, hyperthermia and rhabdomyolysis

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

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