Factor Xa reversal agent
Factor Xa inhibitor reversal agent
- A decoy factor Xa binds and sequesters the “-xaban” anticoagulants
- Restores coagulation in life-threatening bleeding
- Thrombotic risk as anticoagulation is reversed
- Decoy factor Xa that binds the inhibitor, restoring coagulation
Drugs with this mechanism (1)
- Andexanet alfa — Factor Xa decoy that reverses apixaban and rivaroxaban; U.S. sales ended over safety concerns in 2025.
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