Photosensitizer
Photosensitizing agent
- Light exposure generates cytotoxic reactive oxygen species
- Cell death is confined to illuminated, drug-laden tissue
- Systemic photosensitivity until the agent clears
- Generates cytotoxic oxygen species on light exposure
- Prolonged photosensitivity after dosing
Drugs with this mechanism (2)
- Hypericin — St John's wort pigment; a photosensitizer.
- Pseudohypericin — St John's wort constituent; a photosensitizer.
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