Hypericin
SJW constituent
“Hyper rice”
says St John’s wort
What it isSt John’s wort pigment and a photosensitiser.
Why this oneIt is the constituent behind the phototoxicity of the herb.
What limits itIt is also the compound most often standardized on the label, though hyperforin drives the interactions.
FDA-approved for
- St John's wort constituent (not approved)
Off-label
- St John's wort constituent studied for depression and as a photosensitizer
NO BOXED WARNINGS
Principal riskPhotosensitivity
Classes and tags
Clinical profile
Defining liabilityDose- and light-dependent phototoxicity