Leptin receptor agonist
- Hypothalamic satiety signaling → reduced food intake
- Replaces the missing hormone in congenital leptin deficiency
- Little effect in common obesity (leptin resistance)
- Signals satiety — replacement in congenital leptin deficiency
Drugs with this mechanism (1)
- Leptin — Endogenous satiety hormone from fat; deficiency causes severe obesity.
All mechanisms · Open Leptin receptor agonist in the interactive console ↗