KCNQ opener
KCNQ potassium channel opener
- Stabilizes the resting membrane
- ↓ repetitive firing → antiseizure effect
- Urinary retention from bladder smooth-muscle Kv7 opening
- Opens neuronal potassium channels — antiepileptic
- Retinal pigment changes and blue skin discoloration
Drugs with this mechanism (1)
- Ezogabine — KCNQ potassium-channel opener anticonvulsant; withdrawn for pigmentation.
All mechanisms · Open KCNQ opener in the interactive console ↗