gp120 attachment inhibitor
HIV gp120 attachment inhibitor
- Blocks attachment to the CD4 receptor
- Stops entry of virus resistant to other classes
- Acts before co-receptor binding — the earliest step in the entry sequence
- Blocks HIV attachment to CD4
- For heavily treatment-experienced patients
Drugs with this mechanism (1)
- Temsavir — Active fostemsavir metabolite that binds HIV gp120 and blocks attachment; used in regimens for heavily treatment-experienced patients.
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