3CL protease inhibitor
- Prevents polyprotein cleavage → halts SARS-CoV-2 replication
- Blocks the coronavirus main protease, preventing polyprotein cleavage
Drugs with this mechanism (1)
- Nirmatrelvir — The COVID protease inhibitor in Paxlovid; boosted by ritonavir.
All mechanisms · Open 3CL protease inhibitor in the interactive console ↗