Androgen receptor agonist
- ↑ libido, muscle mass and bone density
- Negative feedback suppresses gonadotropins → ↓ spermatogenesis
- Stimulates erythropoiesis → polycythemia risk
- Testosterone replacement — libido, muscle mass, bone density
- Polycythemia, sleep apnea, suppressed spermatogenesis
Drugs with this mechanism (6)
- Danazol — Weak androgen suppressing gonadotropins; used for endometriosis and hereditary angioedema.
- Levonorgestrel — Progestin used in emergency contraception and hormonal IUDs.
- Norethindrone — A common progestin in contraceptives and hormone therapy.
- Norgestrel — Racemic progestin; only the levonorgestrel enantiomer is active. First OTC oral contraceptive.
- Testosterone — Principal androgen for hypogonadism; controlled because of anabolic misuse.
- Testosterone cypionate — Depot androgen for hypogonadism; erythrocytosis and infertility can end treatment.
All mechanisms · Open Androgen receptor agonist in the interactive console ↗