Unknown target
Unknown clinical target
- The clinical effect is established but the molecular target remains unidentified
- A placeholder for mechanisms not yet mapped to a receptor or enzyme
- Clinical effect established; the molecular target is not
- Pyrazinamide is the library’s one genuine unknown: fatty-acid synthase I, ribosomal trans-translation and membrane depolarization by pyrazinoic acid all have support, and none is settled
Drugs with this mechanism (1)
- Pyrazinamide — First-line tuberculosis drug whose mechanism is genuinely contested — fatty-acid synthase I, ribosomal trans-translation, and membrane depolarization by pyrazinoic acid all have support, none settled; hepatotoxicity and hyperuricemia limit it.
All mechanisms · Open Unknown target in the interactive console ↗