SV2A modulator
Synaptic vesicle protein 2A modulator
- Interferes with preparation of presynaptic vesicles for neurotransmitter release
- ↓ glutamate release from rapidly firing neurons
- Broad-spectrum antiepileptic
- Irritability and mood change are common
Drugs with this mechanism (2)
- Brivaracetam — SV2A ligand, a more selective successor to levetiracetam.
- Levetiracetam — Widely used, kinetically clean anticonvulsant; irritability and mood effects common.
All mechanisms · Open SV2A modulator in the interactive console ↗