TNF decoy receptor
TNF-alpha decoy receptor
- Anti-inflammatory across rheumatoid arthritis and psoriasis
- Immunosuppression → infection and TB reactivation risk — screen first
- Decoy receptor binding TNF-alpha
- Reactivation of latent tuberculosis — screen before starting
Drugs with this mechanism (1)
- Etanercept — Soluble TNF receptor-Fc decoy; mops up TNF-α and lymphotoxin-α, unlike the anti-TNF antibodies.
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