Glutathione depletion (CNS and renal)
- Depletes glutathione in CNS and renal tubules
- Neurotoxicity (encephalopathy) and nephrotoxicity
- Depletes glutathione in CNS and renal tubules
- Neurotoxicity (encephalopathy) and nephrotoxicity
Drugs with this mechanism (1)
- Chloroacetaldehyde — Toxic ifosfamide metabolite implicated in encephalopathy and kidney injury; distinct from bladder-toxic acrolein.
All mechanisms · Open Glutathione depletion (CNS and renal) in the interactive console ↗