Digoxin sequestrant
- Reverses life-threatening digoxin toxicity within minutes
- Serum digoxin assays become meaningless after administration (bound drug is still measured)
- Hypokalemia as Na⁺/K⁺-ATPase activity returns
- Antibody fragments bind digoxin, reversing toxicity
- Bound drug still registers on total-level assays
Drugs with this mechanism (1)
- Digoxin immune Fab — Digoxin-sequestering antibody fragments for life-threatening cardiac-glycoside toxicity.
All mechanisms · Open Digoxin sequestrant in the interactive console ↗