Cyanide sulfur donor
- Donates sulfur to rhodanese → converts cyanide to excretable thiocyanate
- A metabolic detox route, distinct from directly binding cyanide
- Donates sulfur to rhodanese → converts cyanide to excretable thiocyanate
- A metabolic detox route, distinct from directly binding cyanide
Drugs with this mechanism (1)
- Sodium thiosulfate — Sulfur-donor cyanide antidote; also protects hearing during pediatric cisplatin therapy.
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