Prostacyclin IP receptor agonist
- Vasodilation and ↓ platelet aggregation → treats pulmonary arterial hypertension
- Headache, flushing, jaw pain, diarrhea
- Pulmonary vasodilation and antiplatelet effect
- Used in pulmonary arterial hypertension
Drugs with this mechanism (3)
- Epoprostenol — Continuous IV prostacyclin for severe pulmonary arterial hypertension; interruption can be fatal.
- Selexipag — Oral prostacyclin-receptor agonist for pulmonary hypertension.
- Treprostinil — Prostacyclin analog for pulmonary hypertension; multiple delivery routes.
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