Progesterone receptor antagonist
- Blocks progesterone support of the endometrium and pregnancy
- Decidual breakdown and uterine sensitization
- Terminates pregnancy by blocking progesterone support
- Also used in Cushing syndrome
Drugs with this mechanism (1)
- Mifepristone — Progesterone/glucocorticoid antagonist; medical abortion and Cushing-syndrome hyperglycemia.
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