Potassium repletion
- Restores membrane excitability and cardiac/neuromuscular function
- The exact opposite of a potassium binder
- Too-rapid repletion → hyperkalemia → arrhythmia
- Replaces depleted potassium
- ⚑ The opposite of a potassium binder — do not confuse repletion with sequestration
- ⚑ Rapid IV administration can be fatal; oral forms cause GI ulceration
- ➔ always dilute, never IV push
Drugs with this mechanism (1)
- Potassium chloride — Standard hypokalemia replacement; oral GI injury and IV errors can be lethal.
All mechanisms · Open Potassium repletion in the interactive console ↗