PI3K-delta inhibitor
- Impairs B-cell-receptor survival signaling → treats B-cell malignancies
- Autoimmune-type toxicities: colitis, hepatitis, pneumonitis
- B-cell malignancies
- Colitis, pneumonitis and hepatotoxicity
Drugs with this mechanism (1)
- Idelalisib — PI3K-delta inhibitor for B-cell malignancies.
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