NOP agonist
Nociceptin receptor agonist
- ↓ dopamine release and context-dependent pain modulation
- Explored for its potential to separate analgesia from mu-opioid reward
- Central pro-nociceptive effects
- ➔ reduced stress-induced analgesia
- Decreased dopamine release NOP
Drugs with this mechanism (1)
- Nociceptin — Endogenous ligand of the NOP opioid-like receptor.
All mechanisms · Open NOP agonist in the interactive console ↗