Metal chelator
Polyvalent metal chelator (antifungal)
- Chelates polyvalent metals required by fungal metalloenzymes
- Inhibits fungal metabolism — distinct from ergosterol-synthesis blockade
- Broad topical antifungal/antibacterial action
- Chelates the polyvalent metals fungal enzymes depend on
- A distinct antifungal mechanism from ergosterol synthesis blockade
Drugs with this mechanism (1)
- Ciclopirox — Non-azole topical antifungal; nail lacquer cures onychomycosis poorly.
All mechanisms · Open Metal chelator in the interactive console ↗