KIT/PDGFRA inhibitor
KIT and PDGFRA kinase inhibitor
- Suppresses gastrointestinal stromal tumors
- Hair and skin depigmentation
- Blocks KIT and PDGFRA kinases
- Suppresses gastrointestinal stromal tumors, including resistance mutations
- A broad-spectrum switch-control inhibitor for later-line GIST
Drugs with this mechanism (1)
- Ripretinib — KIT/PDGFRA switch-control inhibitor for heavily pretreated gastrointestinal stromal tumors; alopecia and hand-foot syndrome are common.
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