Heme detoxification inhibitor
Plasmodial heme detoxification inhibitor
- Blocks the parasite’s conversion of toxic heme into inert hemozoin
- Free heme accumulates and kills the Plasmodium
- Blocks heme detoxification in the parasite food vacuole
Drugs with this mechanism (1)
- Mefloquine — Long-acting antimalarial with well-known neuropsychiatric effects.
All mechanisms · Open Heme detoxification inhibitor in the interactive console ↗