Glucocorticoid receptor modulator
- Dissociated steroid biases signaling toward transrepression (anti-inflammatory) over transactivation (metabolic)
- Anti-inflammatory benefit with less growth suppression and bone toxicity
- Vamorolone in Duchenne muscular dystrophy
Drugs with this mechanism (1)
- Vamorolone — Dissociative glucocorticoid-receptor modulator for Duchenne dystrophy; still suppresses the adrenal axis.
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