FFA4 agonist
Free fatty acid receptor 4 (GPR120) agonist
- The omega-3 fatty acid sensor
- Anti-inflammatory macrophage signaling
- Improved insulin sensitivity
- ↑ GLP-1 secretion from intestinal L cells
- Anti-inflammatory signaling and improved insulin sensitivity
Drugs with this mechanism (2)
- Icosapent ethyl — Purified EPA omega-3 that lowers triglycerides and cardiovascular events.
- Omega-3 fatty acids — Mixed EPA/DHA lowers triglycerides but can raise LDL; OTC products are not equivalent.
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