FAD cofactor: Complex II
- Links the TCA cycle directly to the electron-transport chain
- Derived from riboflavin (vitamin B2)
- FAD is covalently wired into succinate dehydrogenase — TCA cycle and respiratory chain in one enzyme
Drugs with this mechanism (1)
- FAD — Riboflavin-derived redox cofactor; transfers electrons in fatty-acid oxidation and mitochondrial energy production.
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