Factor Xa inhibitor
- Thrombin generation falls
- Anticoagulation without INR monitoring
- A decoy factor Xa exists for bleeding reversal
- Bleeding risk
- Bleeding risk
Drugs with this mechanism (4)
- Apixaban — Factor Xa inhibitor often favored for lower bleeding risk; twice-daily.
- Betrixaban — Discontinued oral factor Xa inhibitor for extended VTE prophylaxis in acutely ill hospitalized patients.
- Edoxaban — Once-daily oral factor Xa inhibitor anticoagulant.
- Rivaroxaban — Once-daily factor Xa inhibitor; convenient but food-dependent at treatment exposure.
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