Ile-tRNA synthetase inhibitor
Isoleucyl-tRNA synthetase inhibitor
- Bacterial protein synthesis fails
- Eradication of staphylococci, including nasal MRSA carriage (topical)
- A target unused by any systemic antibiotic — no cross-resistance
- Blocks bacterial protein synthesis by inhibiting isoleucyl-tRNA synthetase
Drugs with this mechanism (1)
- Mupirocin — Topical isoleucyl-tRNA synthetase inhibitor for impetigo and MRSA decolonization.
All mechanisms · Open Ile-tRNA synthetase inhibitor in the interactive console ↗