ALDH inhibitor
Aldehyde dehydrogenase inhibitor
- Acetaldehyde accumulates when alcohol is consumed
- Flushing, nausea, tachycardia — aversive alcohol reaction
- Flushing, nausea, tachycardia on alcohol exposure
Drugs with this mechanism (1)
- Disulfiram — Aldehyde-dehydrogenase inhibitor causing an aversive reaction to alcohol.
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