CysLT1 antagonist
Cysteinyl leukotriene receptor antagonist
- ↓ bronchoconstriction, mucus and allergic inflammation
- Neuropsychiatric events: agitation, depression, sleep disturbance, suicidality
- Blocks leukotriene signaling in asthma and allergic rhinitis
- Neuropsychiatric effects including mood change and agitation
Drugs with this mechanism (2)
- Montelukast — Leukotriene antagonist for asthma and allergy; neuropsychiatric warning.
- Zafirlukast — Leukotriene receptor antagonist; a 2C9 inhibitor, unlike montelukast.
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