Coenzyme A: acetyl-CoA
- Acetyl-CoA is the hub of fuel metabolism
- Feeds the TCA (tricarboxylic acid) cycle from carbohydrate, fat and protein
- Derived from pantothenate (vitamin B5)
- Pantothenate builds CoA; acetyl-CoA is the two-carbon hub where sugars, fats and ketones interconvert
Drugs with this mechanism (1)
- Coenzyme A — Pantothenate-derived carrier of acyl groups; central to fatty-acid metabolism and cellular energy production.
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