ClC-2 activator
ClC-2 chloride channel activator
- Intestinal chloride and water secretion → softer stool
- Nausea is the signature side effect
- Diarrhea
- Increases intestinal chloride and fluid secretion
- Nausea from the secretory effect
Drugs with this mechanism (1)
- Lubiprostone — Chloride-channel activator for chronic constipation.
All mechanisms · Open ClC-2 activator in the interactive console ↗