Central muscle relaxant
- Reduces central motor and reflex activity → muscle relaxation
- Sedation accompanies the same CNS depression
- The precise molecular target is not established
Drugs with this mechanism (2)
- Metaxalone — Relatively nonsedating muscle relaxant for acute spasm; efficacy evidence is weak.
- Methocarbamol — Sedating central muscle relaxant of uncertain mechanism for acute musculoskeletal spasm.
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