Bile acid sequestrant
- Forces hepatic cholesterol conversion into new bile acids
- ↓ LDL cholesterol
- Constipation and bloating
- Binding is non-selective — other drugs and fat-soluble vitamins too
- Constipation and bloating
- Binding is non-selective — other drugs and fat-soluble vitamins too
Drugs with this mechanism (3)
- Cholestyramine — Bile-acid sequestrant for cholesterol; binds many other drugs.
- Colesevelam — Bile-acid sequestrant that also modestly lowers glucose.
- Colestipol — Nonabsorbed bile-acid sequestrant tablet for LDL lowering or bile-acid diarrhea; binds other drugs.
All mechanisms · Open Bile acid sequestrant in the interactive console ↗