5-HT2C partial agonist
5-HT2C serotonin receptor partial agonist
- Intermediate appetite and mood effects
- Less weight gain than full 5-HT2C blockade
- Effect direction depends on ambient serotonin tone
- Appetite and mood modulation
Drugs with this mechanism (5)
- Aripiprazole — D2 partial agonist; weight-favorable, activating, low prolactin; can cause akathisia.
- Aripiprazole lauroxil LAI — Long-acting aripiprazole prodrug injection for schizophrenia; requires a loading strategy.
- Aripiprazole lauroxil LAI — Rapid-start aripiprazole lauroxil injection used only to initiate Aristada treatment.
- Aripiprazole monohydrate LAI — Extended-interval aripiprazole LAI for schizophrenia and bipolar maintenance.
- Aripiprazole monohydrate LAI — Long-acting aripiprazole for schizophrenia and bipolar maintenance; akathisia remains prominent.
All mechanisms · Open 5-HT2C partial agonist in the interactive console ↗