KENALOG
Pronunciation: trye-am-SIN-oe-loen


What it isGlucocorticoid-receptor agonist; intra-articular, intramuscular, intranasal and topical treatment of inflammation.
Why this oneA long-lived intra-articular depot effect is its distinguishing niche, while topical and nasal forms cover local inflammation.
What limits itRepeated joint injections can damage cartilage; systemic absorption can still suppress the adrenal axis and raise glucose.
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| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Nasal allergy symptoms (OTC triamcinolone acetonide nasal spray) | Adults & children ≥12 yr | 2 sprays each nostril QD | 1 spray each nostril QD after symptoms improve | 2 sprays each nostril QD |
| Nasal allergy symptoms (OTC) | Children 6 to <12 yr | 1 spray each nostril QD | 1 spray each nostril QD after improvement | 2 sprays each nostril QD |
| Nasal allergy symptoms (OTC) | Children 2 to <6 yr | 1 spray each nostril QD | 1 spray each nostril QD | 1 spray each nostril QD |
Renal Undefined
Hepatic Undefined
Available strengths
Pregnancy Undefined
Lactation Undefined
| Strength | #/mo | generic $/unit | CostPlus | |
|---|---|---|---|---|
| 0.025 % | cream | per unit | not offered | |
| 0.1 % | cream | per unit | not offered | |
| 0.5 % | cream | per unit | not offered | |
| 0.025 % | ointment | per unit | not offered | |
| 0.1 % | ointment | per unit | not offered | |
| 0.5 % | ointment | per unit | not offered |
Other forms: Triamcinolone injection (KENALOG-40)
Generic entry1982
NO BOXED WARNINGS
Principal riskAdrenal suppression with prolonged systemic use
Legacy pregnancy categoryC
Defining liabilityHyperglycemia, infection, osteoporosis and potentially severe mood, sleep or psychotic effects.
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