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Triamcinolone

KENALOG

Pronunciation: trye-am-SIN-oe-loen

Triamcinolone ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Triamcinolone ballicule
Triamcinolone KENALOG mascot mnemonic cartoon
Visual mnemonic: Triamcinolone mascot
“Ken-log, Try and sin, alone”
moon face → corticosteroid

What it isGlucocorticoid-receptor agonist; intra-articular, intramuscular, intranasal and topical treatment of inflammation.

Why this oneA long-lived intra-articular depot effect is its distinguishing niche, while topical and nasal forms cover local inflammation.

What limits itRepeated joint injections can damage cartilage; systemic absorption can still suppress the adrenal axis and raise glucose.

Triamcinolone molecular structure (skeletal formula)
Molecular structure: Triamcinolone

FDA-approved for

FDA label

FDA dosingPopulationStartTargetMax
Nasal allergy symptoms (OTC triamcinolone acetonide nasal spray)Adults & children ≥12 yr2 sprays each nostril QD1 spray each nostril QD after symptoms improve2 sprays each nostril QD
Nasal allergy symptoms (OTC)Children 6 to <12 yr1 spray each nostril QD1 spray each nostril QD after improvement2 sprays each nostril QD
Nasal allergy symptoms (OTC)Children 2 to <6 yr1 spray each nostril QD1 spray each nostril QD1 spray each nostril QD

Renal Undefined

Hepatic Undefined

Instructions

Available strengths

Cautions

Pregnancy Undefined

Lactation Undefined

Cost

Triamcinolone (KENALOG)
Strength#/mogeneric $/unitCostPlus
0.025 %creamper unitnot offered
0.1 %creamper unitnot offered
0.5 %creamper unitnot offered
0.025 %ointmentper unitnot offered
0.1 %ointmentper unitnot offered
0.5 %ointmentper unitnot offered
NADAC is a voluntary CMS survey of what retail community pharmacies pay for the drugs they stock. Triamcinolone is dispensed outside retail pharmacies, so it rarely appears on surveyed invoices.

Other forms: Triamcinolone injection (KENALOG-40)

Generic entry1982

NO BOXED WARNINGS

Principal riskAdrenal suppression with prolonged systemic use

Classes and tags

Clinical profile

Therapeutic safety burden0 / 4
Overdose danger2 / 4
Weight-gain liability1 / 4
Sedation liability0 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk2 / 4

Legacy pregnancy categoryC

Defining liabilityHyperglycemia, infection, osteoporosis and potentially severe mood, sleep or psychotic effects.

Open Triamcinolone in the interactive console ↗

Memory aids: interaction avatars

Triamcinolone Box: minimal PK interactions avatar mnemonic
Box: minimal PK interactions

Open Triamcinolone in the interactive console ↗