Withdrawn from the market (safety)
Ticarcillin
TIMENTIN
“Ticker (on) ceiling”
What it isExtended-spectrum carboxypenicillin, combined with clavulanate as TIMENTIN; Pseudomonas and mixed intra-abdominal infection.
Why this oneAntipseudomonal cover in a beta-lactam, with clavulanate restoring activity against beta-lactamase producers.
What limits it⛑ Discontinued in the U.S. — piperacillin-tazobactam replaced it. High sodium load, hypokalemia and platelet dysfunction at high dose.
NO BOXED WARNINGS
Principal riskDiscontinued in the U.S.; sodium load and platelet dysfunction
Classes and tags
Clinical profile
Legacy pregnancy categoryB
Defining liabilityHypersensitivity, sodium load and renal-exposure-dependent neurotoxicity
Open Ticarcillin in the interactive console ↗
Memory aids: interaction avatars
