Salvinorin A
salvia
What it isNon-nitrogenous kappa opioid agonist from Salvia divinorum.
Why this oneIt is the most potent naturally occurring hallucinogen and the only one acting through kappa rather than 5-HT2A.
What limits itIntense brief dissociation with a high risk of injury. No therapeutic use; it is the tool compound for kappa research.
FDA-approved for
- kappa-opioid psychedelic (not approved)
NO BOXED WARNINGS
Principal riskIntense brief dissociation with a high risk of injury
Classes and tags
Clinical profile
Defining liabilityRapid profound dissociation with unpredictable behavior