Psilocin
active
What it isThe active dephosphorylated metabolite of psilocybin, a 5-HT2A agonist.
Why it mattersIt is the species that actually acts — psilocybin is a prodrug converted by intestinal phosphatase.
What it changesIts shorter half-life than the parent dosing suggests explains the sharp onset after ingestion.
FDA-approved for
- active metabolite of psilocybin (not approved)
NO BOXED WARNINGS
Principal riskIts shorter half-life than the parent dosing suggests explains the sharp onset after ingestion