Ballicules.com

Pregnenolone

neurosteroid

Pregnenolone ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Pregnenolone ballicule

What it isThe precursor from which all steroid hormones and neurosteroids are made.

Why this oneIts position at the head of the pathway is why it is marketed as a broad hormonal supplement.

What limits itSupplementation raises unpredictable downstream hormones. Evidence for the promoted uses is weak.

Pregnenolone molecular structure (skeletal formula)
Molecular structure: Pregnenolone

Available strengths

NO BOXED WARNINGS

Principal riskSupplementation raises unpredictable downstream hormones

Classes and tags

Clinical profile

Therapeutic safety burden1 / 4
Weight-gain liability0 / 4
Sedation liability0 / 4
Direct muscarinic antagonism0 / 4

Defining liabilityLimited long-term endocrine and reproductive safety evidence

Active metabolites

Open Pregnenolone in the interactive console ↗