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Picrotoxin

convulsant

Picrotoxin ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Picrotoxin ballicule

What it isGABA-A channel blocker; a research convulsant.

Why this oneIt defined the GABA-A chloride channel pore as distinct from the benzodiazepine and barbiturate sites.

What limits itConvulsant with no therapeutic use.

Picrotoxin molecular structure (skeletal formula)
Molecular structure: Picrotoxin

NO BOXED WARNINGS

Principal riskSeizures; no therapeutic use

Classes and tags

Clinical profile

Direct muscarinic antagonism0 / 4

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