PEG 3350/ electrolytes
GOLYTELY
What it isNonabsorbed osmotic laxative balanced with electrolytes; colonoscopy bowel preparation.
Why this oneThe balanced solution permits complete lavage with little net electrolyte movement, useful in renal or cardiac disease.
What limits itLarge volume and salty taste impair completion; nausea, bloating and aspiration are practical hazards.
FDA label
Read the full label on DailyMed ↗
| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Colon cleansing before colonoscopy/barium enema | adults | 8 oz every 10 minutes | until 4 liters consumed or rectal effluent is clear | 4 liters |
Renal Use with caution (risk of renal injury); ensure hydration and consider baseline/post-procedure labs.
Hepatic Undefined
Do not take other laxatives concurrently.
Instructions
- Reconstitute powder with water before ingestion; do not add starch-based thickeners.
- Begin early evening the day before colonoscopy; drink 8 oz every 10 minutes.
- Correct fluid/electrolyte abnormalities before use; consume only clear liquids.
- Do not take other oral medications within 1 hour of dosing.
Available strengths
- sol 236/2.97/6.74/5.86/22.74, 240/2.98/6.72/5.84/22.72, 420/1.48/5.72/11.2 g/bot
Contraindications
- Gastrointestinal (GI) obstruction
- Bowel perforation
- Toxic colitis or toxic megacolon
- Gastric retention
- Ileus
Cautions
- Fluid and electrolyte abnormalities
- Cardiac arrhythmias
- Seizures
- Renal impairment / concomitant nephrotoxic drugs
- Mucosal ulcerations (may confound IBD findings)
- Aspiration risk
- Hypersensitivity reactions including anaphylaxis
Adverse reactions
- Nausea
- Abdominal fullness
- Bloating
- Abdominal cramps
- Vomiting
- Anal irritation
Pregnancy No animal reproduction studies; use only if clearly needed.
Lactation Undefined
Cost
| Strength | #/mo | generic $/unit | CostPlus | |
|---|---|---|---|---|
| 236/2.97/6.74/5.86/22.74 g/bot | sol | per unit | not offered | |
| 240/2.98/6.72/5.84/22.72 g/bot | sol | per unit | not offered | |
| 420/1.48/5.72/11.2 g/bot | sol | per unit | not offered |
NO BOXED WARNINGS
Principal riskFluid and electrolyte abnormalities; arrhythmias and seizures
Classes and tags
Clinical profile
Defining liabilityDiarrhea, bloating and abdominal cramping