NAD
from niacin/ nicotinamide
What it isNicotinamide adenine dinucleotide, the redox coenzyme derived from niacin.
Why it mattersEvery dehydrogenase step in catabolism cycles NAD+/NADH; it is also the substrate consumed by sirtuins and PARPs.
What it changesNiacin deficiency (pellagra) and the alcohol-driven NADH excess that suppresses gluconeogenesis are its two classic clinical faces.
NO BOXED WARNINGS