Moricizine
ETHMOZINE
What it isClass I antiarrhythmic; withdrawn.
Why this oneIt was studied in CAST-II as a supposedly safer class I agent.
What limits itCAST-II found excess early mortality, confirming the class hazard. Withdrawn.
FDA-approved for
- ventricular arrhythmias (withdrawn) (1990)
⚠ BOXED WARNING
- Proarrhythmia and excess mortality after myocardial infarction
Classes and tags
Clinical profile
Defining liabilityProarrhythmia and increased mortality after myocardial infarction