Mivacurium
MIVACRON
What it isShort-acting non-depolarizing blocker hydrolyzed by plasma cholinesterase; brief procedures.
Why this oneIt is the only non-depolarizing agent short enough to substitute for succinylcholine in short cases.
What limits itProlonged block in pseudocholinesterase deficiency, the same trap as succinylcholine. Histamine release.
FDA-approved for
- neuromuscular blockade (surgery) (1992)
NO BOXED WARNINGS
Principal riskProlonged block in pseudocholinesterase deficiency
Classes and tags
Clinical profile
Legacy pregnancy categoryC
Defining liabilityRespiratory paralysis, histamine hypotension and cholinesterase-dependent prolonged blockade