Methaqualone
QUAALUDE
“Quiet Interlude (for) Metal aqua-lung”
What it isSedative-hypnotic GABA-A modulator; withdrawn worldwide.
Why this oneIt was widely prescribed as a non-barbiturate hypnotic.
What limits itDependence and a lethal overdose profile led to global withdrawal. Illicit manufacture persists in some regions.
FDA-approved for
- insomnia and anxiolysis (withdrawn 1984; now Schedule I)
NO BOXED WARNINGS
Principal riskWithdrawn; dependence and lethal overdose