Meclizine
ANTIVERT
Pronunciation: MEK-li-zeen
“McLizard is Anti-vertigo”
What it isCentrally acting H1 antihistamine; vertigo and motion sickness.
Why this oneIt works on vestibular nausea, where ondansetron does not.
What limits itSedation and fall risk, so poor in the elderly. It suppresses vestibular compensation, so it should not be continued for weeks.
FDA-approved for
- vertigo/motion sickness (~1957)
FDA label
Read the full label on DailyMed ↗
| FDA dosing | Population | Start | Target | Max |
|---|---|---|---|---|
| Motion sickness prevention | Adults & children ≥12 yr | 1–2 tablets QD | 1–2 tablets QD | 2 tablets QD |
Renal Undefined
Hepatic Undefined
Instructions
- Take first dose ½ to 1 hour before starting activity/travel.
- Do not take more than directed.
Available strengths
- tab 12.5, 25, 50 mg
- chew tab 25 mg
- ODT 25 mg
- powder 50 mg
Pregnancy Undefined
Lactation Undefined
Cost
Meclizine (ANTIVERT)
What pharmacies pay · NADAC 9/30/26
Generic entry1982
NO BOXED WARNINGS
Principal riskSedation and fall risk
Classes and tags
Clinical profile
Legacy pregnancy categoryC
Defining liabilitySedation, QT prolongation, extrapyramidal symptoms or anticholinergic toxicity vary by receptor target.
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