Not available in the U.S.
Lobeglitazone
DUVIE
What it isThiazolidinedione PPAR-gamma agonist that improves peripheral insulin sensitivity.
Why this oneApproved in South Korea (Duvie) for type 2 diabetes, delivering glitazone-class glycemic benefit at low milligram doses.
What limits itShares TZD-class risks of fluid retention, heart failure exacerbation, weight gain and fracture, and is not FDA-approved.
NO BOXED WARNINGS
Principal riskNo FDA boxed warning.