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Indacaterol

ARCAPTA

Pronunciation: in-da-KA-ter-ol (ar-KAP-ta)

Indacaterol ballicule: receptor binding, kinetics and half-life diagram
Mechanism of action: Indacaterol ballicule

What it isOnce-daily long-acting beta-2 agonist; COPD maintenance.

Why this oneTwenty-four-hour bronchodilation with a rapid onset, unusual for a LABA.

What limits itNever as monotherapy in asthma. Cough immediately after inhalation is characteristic.

Indacaterol molecular structure (skeletal formula)
Molecular structure: Indacaterol

FDA-approved for

NO BOXED WARNINGS

Principal riskNever as monotherapy in asthma; post-inhalation cough

Classes and tags

Clinical profile

Therapeutic safety burden1 / 4
Overdose danger2 / 4
Weight-gain liability0 / 4
Sedation liability0 / 4
QT / Torsades0 / 4
Direct muscarinic antagonism0 / 4
Embryofetal risk2 / 4

Defining liabilityAdrenergic cardiovascular effects and paradoxical bronchospasm

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